Research demonstrator · synthetic data · not for clinical use

Fewer interruptions for clinicians. No alert hidden.

Major alerts stay interruptive. Every decision is explained, traced and can be replayed.

See the medication risk that builds up — not just the pairs.

PolyScope is an explained polypharmacy review. It shows how risk converges as drugs stack up, in the context of the patient's kidney and liver function, lab results and conditions — and it says clearly what it could not assess.

Free, for everyone who reviews medicines

No price, no advertising, no commercial purpose — for clinicians, pharmacists, researchers and healthcare institutions alike.

  • Free, no advertising
  • English · עברית · Français
  • Can run without internet

Interaction checkers look at drugs two at a time.

Several drugs that each add a little bleeding risk, kidney strain or QT prolongation can look acceptable pair by pair. Together, in an older patient with reduced kidney function, they may not be. And when every pair is flagged, the alert that matters is easy to miss.

Pairwise checker
moderateWarfarin + Citalopram
moderateCitalopram + Ibuprofen
majorWarfarin + Ibuprofen

Three separate alerts, no patient context.

PolyScope
Bleeding riskhigh
Converging across 3 drugs
Kidney riskhigh
Ibuprofen, amplified by eGFR 38 (measured 3 days ago)
Not assessed: liver risk — ALT not available
Illustrative example — synthetic patient, 78 years old, on warfarin, citalopram and ibuprofen.

Five cases, and what you would see

Synthetic patients. Each picture is the real screen of the demonstrator.

1

Brand names, in three languages

Eliquis, its Hebrew name אליקוויס, or Depalept: clinicians type what is on the box. PolyScope finds the active substance — apixaban, valproic acid — and works on that.

2

A combination that pair checkers miss

75 years old, atrial fibrillation and chronic kidney disease, on apixaban and valproic acid. PolyScope points to an added bleeding risk, clearly marked as proposed, with its source one tap away.

3

Eight drugs, four problems

84 years old, kidney function at 25, eight drugs. Instead of one alert per pair: the kidney, bleeding across four drugs, potassium across three, and the rest. Major alerts are always shown. The missing potassium value is named.

4

A lab result that is too old

The same patient, but the kidney result is four months old. PolyScope says so, and asks for a new value instead of deciding on old data. Doubt never makes an alert disappear.

5

Nothing to flag — said plainly

Lactulose and pindolol. No problem found, and PolyScope says exactly that — including the one pair its source has not graded. Missing data is never presented as safety.

New in November 2026

Medication review

For each medicine: why it was started, when, and when it should be looked at again. PolyScope asks the questions a review needs — no recorded reason, a review date passed, a usual treatment length exceeded, a drug that may be treating the side effect of another. These questions are proposals, not yet activated.

Diet and administration

Grapefruit, alcohol, salt substitutes, dairy and calcium, when to take each medicine and which ones to take hours apart — taken from each drug's own label. It asks about the diet when it matters for this patient. This advice is a proposal, shown on the screen only — never in the report for the patient.

A report for the consultation

The medicines entered, the information still missing and questions with their sources — ready to print or copy, to bring to the doctor or pharmacist. It contains no diet or treatment advice.

What PolyScope does

∑

Cumulative risk

Adds up each drug's contribution to the same risk — bleeding, kidney, QT, sedation, anticholinergic load, serotonin, potassium — across the whole prescription.

⚕

Patient context

Takes the patient's conditions and dated lab results into account, and flags values too old to rely on.

⌕

Every alert explained

Which drugs contribute, through which mechanism, on which sources — and what to check next.

?

Unknown is not safe

When information is missing, PolyScope says so instead of staying silent.

Rx

Brand names

Type the name on the box — in English, Hebrew or French. The active substance is found for you.

↻

Medication review

Why each drug was started, when to look at it again, and the questions a review should ask.

◔

Diet and administration

Food, drink and supplement advice from each drug's label, and which medicines to take apart.

⌂

Inside the hospital

A version runs entirely inside a hospital's own network, with no internet connection.

How it works

  1. 1

    Choose a patient

    A synthetic patient from a cohort of 2,000 — or your own fictitious patient: age, sex, a few lab values.

  2. 2

    Build the prescription

    Up to twenty drugs and twenty additional conditions, typed by brand or generic name.

  3. 3

    Read the risk picture

    Explained alerts, shown side by side with what a pairwise checker would report.

Who it can help

Hospital pharmacists and physicians

Medication review at admission and discharge, in internal medicine and geriatrics.

Family doctors and practice pharmacists

Structured medication reviews: reasons for each drug, review dates, diet advice.

Health systems and health funds

Fewer interruptions for clinicians, with every alert still there.

EHR and drug-knowledge vendors

A patient-aware layer on top of the interaction alerts you already provide. Let's talk.

Who it is for

Hospital pharmacists and physicians, for medication review at admission and discharge — especially in internal medicine and geriatrics, where clinical pharmacist time is scarce. We are looking for a hospital partner for a first pilot.

Status

  • Research demonstrator, pre-regulatory. Not a medical device.
  • Runs on synthetic patients only — never on real patient data.
  • Its clinical content is illustrative and still to be reviewed by clinicians.
  • Not to be used for clinical decisions.

Questions

Is it really free?

Yes. PolyScope is free, without advertising and for no commercial purpose — for individuals and for healthcare institutions. Some of its data come from sources licensed for non-commercial use only.

Does it use real patient data?

No. The demonstrator runs only on synthetic patients. Never enter real patient information.

Is it a medical device?

No. It is a research demonstrator, before any regulatory step. It must not be used for clinical decisions.

Where do the drug data come from?

Public sources, named on every alert: DDInter 2.0, openFDA drug labels, SIDER 4.1, TWOSIDES and the FDA's tables of drug metabolism. Licences and attributions are in the terms of access.

Which languages?

English, Hebrew (right to left) and French, for the screens and for brand names. The consultation report is in English for now.

Can it run without internet?

Yes. A version runs entirely inside a hospital's network, with no internet connection and no data leaving it.

How do I get access?

Request access with your name, organisation and profession. Each request is read by a person; you then receive your sign-in. Access is personal.

Can I suggest a case or report an error?

Please do, at fred@polyscoperx.com. Comments from pharmacists and prescribers are what makes it better.

Access is reviewed

The demonstrator is open to healthcare professionals, researchers and partners. Send a request: your account is activated once it has been reviewed.

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